Synthesis and anti-cancer activity of dinuclear platinum(II) complexes containing bis(thioalkyl)dicarba-closo-dodecaborane(12) ligands.
نویسندگان
چکیده
A series of novel, dinuclear (2,2':6',2''-terpyridine)platinum(ii) complexes containing bis(thioalkyl)-dicarba-closo-dodecaborane(12)(carborane) ligands were prepared and characterised, and their preliminary anti-cancer characteristics have been determined in vitro; the complexes are the first examples of bis-intercalator complexes containing a boron-rich carborane cage.
منابع مشابه
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Information about steric hindrance caused by substituents at phosphorus atoms is of great importance in understanding the chemi cal reactivity of organophosphorus compounds and their ability to act as ligands for tran sition metals [1]. Among dicarba-c/oso-dodecaborane(12) derivatives, 1-phenyl-1,2-dicarbac/oso-dodecaborane( 12) has been regarded as too bulky for the preparation of the corres...
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ورودعنوان ژورنال:
- Dalton transactions
دوره 17 شماره
صفحات -
تاریخ انتشار 2005